Heritability and Genome-Wide Linkage Scan of Subjective Happiness
نویسندگان
چکیده
منابع مشابه
Heritability and genome-wide linkage scan of subjective happiness.
Causes of individual differences in happiness, as assessed with the Subjective Happiness Scale, are investigated in a large of sample twins and siblings from the Netherlands Twin Register. Over 12,000 twins and siblings, average age 24.7 years (range 12 to 88), took part in the study. A genetic model with an age by sex design was fitted to the data with structural equation modeling in Mx. The h...
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BACKGROUND Arterial stiffness and mean arterial pressure variably contribute to systolic hypertension and increased cardiovascular risk. However, few prior community-based studies have evaluated the genetics of arterial stiffness and separate mean and pulsatile components of blood pressure. METHODS AND RESULTS Using arterial tonometry, we evaluated heritability and linkage of forward and refl...
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BACKGROUND Plasma triglyceride concentration is known to be a significant risk factor for cardiovascular disease (CVD). Previous studies have found that the level of triglycerides is strongly influenced by genetic factors. METHODS To identify quantitative trait loci influencing triglycerides, we conducted a genome-wide linkage scan on data from 485 Australian adult dizygotic twin pairs. Prior...
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Domestication and selection are processes that conserve the pattern of genetic diversities between and within populations. Identification of genomic regions that are targets of selection for phenotypic traits is one of the main aims of research in animal genetics. An approach for identifying divergently selected regions of the genome is to compare FST values among loci to estimate the genetic v...
متن کاملHeritability and Preliminary Genome-Wide Linkage Analysis of Arsenic Metabolites in Urine
BACKGROUND Arsenic (III) methyltransferase (AS3MT) has been related to urine arsenic metabolites in association studies. Other genes might also play roles in arsenic metabolism and excretion. OBJECTIVE We evaluated genetic determinants of urine arsenic metabolites in American Indian adults from the Strong Heart Study (SHS). METHODS We evaluated heritability of urine arsenic metabolites [per...
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ژورنال
عنوان ژورنال: Twin Research and Human Genetics
سال: 2010
ISSN: 1832-4274,1839-2628
DOI: 10.1375/twin.13.2.135